The use of hydrocarbon oil collectors is an important means to optimize the slurry preparation effect of coal flotation and achieve efficient separation where there are few studies focused on the impact of collector kinetic energy. In this study, an improved flotation machine and a single kerosene droplet-slime particle collision test system were used to analyze the change of collector kinetic energy under different energy input factors and its impact on the collector-slime adsorption rate. With the increase of mixing time and energy input, the adsorption firstly increases to the maximum then gradually decreases as it is a physical process. When it progressively reaches the saturation state, the dynamic balance of adsorption and desorption is broken with the continuous input of energy. Which will pull the adsorbed kerosene desorb again, resulting in the decrease in adsorption rate, the maximum adsorption rate is 79.82%, under the 40 s mixing time. The change of impeller speed also changes the kinetic energy of the collectors. As the dispersion of particles and reagents increases, the collision probability increases and the adsorption rate increases. When the impeller speed increases from 500 r/min to 700 r/min, the adsorption rate of the collector slime will increase from 78.11% to 79.82%. This research results explore the influence of collector kinetic energy on the adsorption rate from the perspective of multiple variable factors. Which can provide theoretical reference for the influence of collector kinetic energy on the mechanism of slime slurry mixing.